External validation

The succes of prediction models in clinical practise highly depends on continuous validation by clinical studies. External validation is essential to define recommendations for clinical use, reveal relevant limitations, and contribute to the continuous process of updating and improving the model.

As the developers of the ARVC risk calculator we recognize this importance, and appreciate the time and effort of researchers who independently validate this calculator in their cohort. We aim to keep track of all these studies to have a complete, unbiased, and up-to-date overview of the available evidence. As we believe this may be equally relevant to all those using the calculator, we have listed all studies known to us below. Please contact us if you notice a study missing.

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External validation publications:

Casella, M., Gasperetti, A., Gaetano, F., Busana, M., Sommariva, E., Catto, V., et al. (2020). Long-term follow-up analysis of a highly characterized arrhythmogenic cardiomyopathy cohort with classical and non-classical phenotypes-a real-world assessment of a novel prediction model: does the subtype really matter. Europace, 22(5), 797–805. http://doi.org/10.1093/europace/euz352

Aquaro, G. D., De Luca, A., Cappelletto, C., Raimondi, F., Bianco, F., Botto, N., et al. (2020). Prognostic Value of Magnetic Resonance Phenotype in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy. Journal of the American College of Cardiology, 75(22), 2753–2765. http://doi.org/10.1016/j.jacc.2020.04.023

Gasperetti, A., Russo, Dello, A., Busana, M., Dessanai, M., Pizzamiglio, F., Saguner, A. M., et al. (2020). Novel risk calculator performance in athletes with arrhythmogenic right ventricular cardiomyopathy. Heart Rhythm, 17(8), 1251–1259. http://doi.org/10.1016/j.hrthm.2020.03.007

Aquaro, G. D., De Luca, A., Cappelletto, C., Raimondi, F., Bianco, F., Botto, N., et al. (2020). Comparison of different prediction models for the indication of implanted cardioverter defibrillator in patients with arrhythmogenic right ventricular cardiomyopathy. ESC Heart Failure. http://doi.org/10.1002/ehf2.13019